Mathematical Models for Sleep-Wake Dynamics: a Comparison

نویسندگان

  • A. C. Skeldon
  • D.-J. Dijk
  • G. Derks
چکیده

Sleep is essential for the maintenance of human life, yet many features of sleep are poorly understood and mathematical models are an important tool for probing proposed biological mechanisms. The most well-known mathematical model of sleep regulation, the two-process model, models the sleep-wake cycle by two oscillators: a circadian oscillator and a homeostatic oscillator. An alternative, more recent, model considers the reciprocal interaction of sleep promoting neurons and the ascending arousal system regulated by homeostatic and cir-

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تاریخ انتشار 2013